| MICROSCOPIC TECHNIQUES | HYPERLINK to PAPER OR ABSTRACT | TITLE | ABSTRACT | Journal | Volume | ISSUE | MTH | YEAR | CELL LINE | MAIN AUTHOR | CONTRIBUTING AUTHORS | KEYWORDS | MATERIALS & METHODS |
| Spnning Disc Confocal | 932 | Dynamic Fgf signaling couples morphogenesis and migration in the zebrafish lateral line primordium | The collective migration of cells in the form of cohesive tissues is a hallmark of both morphogenesis and repair. The extrinsic cues that direct these complex migrations usually act by regulating the dynamics of a specific subset of cells, those at the le | Development | 135 | 16 | July | 2008 | Lecaudey, Virginie | Virginie Lecaudey, Gulcin Cakan-Akdogan, William H. J. Norton and Darren Gilmour | Lateral line primordium, Zebrafish, Collective migration, Fgf, Rosette morphogenesis | ||
| Spnning Disc Confocal | 944 | Mob4 plays a role in spindle focusing in Drosophila S2 cells | The characteristic bipolar shape of the mitotic spindle is produced by the focusing of the minus ends of microtubules at the spindle poles. The focus is maintained by the centrosome, a microtubule-nucleating organelle, as well as by proteins that are capa | Journal of Cell Science | 121 | 8 | April | 2008 | Trammell, Matthew A. | Matthew A. Trammell, Nicole M. Mahoney, David A. Agard and Ronald D. Vale | RNAi, Centrosome, Microtubule, Kinetochore, y-tubulin | ||
| Spnning Disc Confocal | 898 | Whole genome functional analysis identifies novel
components required for mitotic spindle integrity in human cells |
Background: The mitotic spindle is a complex mechanical
apparatus required for accurate segregation of sister chromosomes during mitosis. We designed a genetic screen using automated microscopy to discover factors essential for mitotic progression. Usin |
Genome Biology | 9 | 2 | February | 2008 | HeLa and U2OS | Daniel R Rines | Daniel R Rines, Maria Ana Gomez-Ferreria, Yingyao Zhou, Paul DeJesus, Seanna Grob, Serge Batalov, Marc Labow, Dieter Huesken, Craig Mickanin, Jonathan Hall, Mischa Reinhardt, Francois Natt, Joerg Lange, David J Sharp, Sumit Chanda, Jeremy S Caldwell | In brief, 80 nmol of the siRNA was diluted in 500 μl of OptiMem (Invitrogen) and placed in a 35 mm glass bottom dish (MatTek Corporation, Ashland, MA). |
|
| Spnning Disc Confocal | 930 | EGF-induced Enhancement of Glioblastoma Cell Migration in 3D Arises from Intrinsic Increase in Speed but Extrinsic Matrix- and Proteolysis-dependent Increase in Persistence | Epidermal growth factor (EGF) receptor-mediated cell migration plays a vital role in invasion of many tumor types. EGF receptor ligands increase invasiveness in vivo, but it remains unclear how consequent effects on intrinsic cell motility behavior versus | Molecular Biology of the Cell | July | 2008 | Kim, Hyung-Do | Hyung-Do Kim, Tiffany W. Guo, Angela P. Wu, Alan Wells, Frank B. Gertler, Douglas A. Lauffenburger | EGF, gliobastoma, cell motility, migration |