Technical Reference #942

Glass Bottom Culture Dishes

This study used MatTek product(s):

Citation in paper containing MatTek reference:
MatTek Plates

942.

The Nucleolin Targeting Aptamer As1411 Destabilizes Bcl-2 Messenger Rna In Human Breast Cancer Cells S Soundararajan; W Chen; EK Spicer; N Courtenay-Luck; and DJ Fernandes, Medical University of South Carolina, Cancer Research, 68(942), (2008)
Link To Paper

Abstract:
We sought to determine whether nucleolin a bcl-2 mRNA-binding protein has a role in the regulation of bcl-2 mRNA stability in MCF-7 and MDA-MB-231 breast cancer cells. Furthermore we examined the efficacy of the aptamer AS1411 in targeting nucleolin an

Keywords:
breast neoplasms; Bcl-2; oligodeoxyribonucleotides; aptamers; phosphoproteins

Materials & Methods:
Cells were grown on MatTek plates (MatTek Corp.).

Microscopic Technique
Confocal Microscopy

Cell Type(s)
MCF10A