Technical Reference #930

Glass Bottom Culture Dishes

This study used MatTek product(s):

Citation in paper containing MatTek reference:
glass-bottom cell culture dishes (MatTek; Ashland; MA)

930.

Egf-Induced Enhancement Of Glioblastoma Cell Migration In 3D Arises From Intrinsic Increase In Speed But Extrinsic Matrix- And Proteolysis-Dependent Increase In Persistence Hyung-Do Kim; Tiffany W. Guo; Angela P. Wu; Alan Wells; Frank B. Gertler; Douglas A. Lauffenburger, Massachusetts Institute of Technology, Molecular Biology of the Cell, 19(930), (2008)
Link To Paper

Abstract:
Epidermal growth factor (EGF) receptor-mediated cell migration plays a vital role in invasion of many tumor types. EGF receptor ligands increase invasiveness in vivo but it remains unclear how consequent effects on intrinsic cell motility behavior versus

Keywords:
EGF; gliobastoma; cell motility; migration

Materials & Methods:
The matrix-cell solution was placed on glass-bottom cell culture dishes (MatTek; Ashland MA) and polymerized for 1 hour at 37ºC.

Microscopic Technique
Confocal Microscopy, Spinning Disc

Cell Type(s)
U87MG