Technical Reference #844

Glass Bottom Culture Dishes

This study used MatTek product(s):

Citation in paper containing MatTek reference:
MatTek glass bottom culture dishes (MatTek Corp.; Ashland; MA)

844.

The E7 Protein Of The Cottontail Rabbit Papillomavirus Immortalizes Normal Rabbit Keratinocytes And Reduces Prb Levels; While E6 Cooperates In Immortalization But Neither Degrades P53 Nor Binds E6Ap Tina Ganzenmueller; Markus Matthaei; Peter Muench; Michael Scheible; Angelika Iftner; Thomas Hiller; Natalie Leiprecht; Sonja Probst; Frank Stubenrauch; Thomas Iftner, Universitaetsklinikum Tuebingen, Virology, 372(844), (2008)
Link To Paper

Abstract:
Human papillomaviruses (HPVs) cause cervical cancer and are associated with the development of non-melanoma skin cancer. A suitable animalmodel for papillomavirus-associated skin carcinogenesis is the infection of domestic rabbits with the cottontail ra

Keywords:
P53 protein; Retinoblastoma protein; Human papillomavirus; Cottontail rabbit papillomavirus; E6; E7; Keratinocytes; Immortalization; Rabbit; E6AP

Materials & Methods:
For indirect immunofluorescence microscopy analysis cells were grown on MatTek glass bottom culture dishes (MatTek Corp. Ashland MA)

Microscopic Technique
Fluorescence Microscopy, Immunofluorescence

Cell Type(s)
HPV16, HPV18 E6, CRPV LE6 and SE6