Technical Reference #830

Glass Bottom Culture Dishes

This study used MatTek product(s):

Citation in paper containing MatTek reference:
Cell-Tak cell and tissue adhesive (BD Biosciences; San Jose; CA)-coated MatTek (Ashland; MA) dishes

830.

Damage-Induced Activation Of Erk1/2 In Cochlear Supporting Cells Is A Hair Cell Death-Promoting Signal That Depends On Extracellular Atp And Calcium Manuela Lahne and Jonathan E. Gale, University College London, The Journal of Neuroscience, 28(830), (2008)
Link To Paper

Abstract:
Acoustic overstimulation and ototoxic drugs can cause permanent hearing loss as a result of the damage and death of cochlear hair cells.

Keywords:
cochlea; ototoxicity; calcium signaling; purinergic receptors; cell– cell communication; ERK

Materials & Methods:
The cochlear turns were placed onto Cell-Tak cell and tissue adhesive (BD Biosciences San Jose CA)-coated MatTek (Ashland MA) dishes.

Microscopic Technique
Confocal Microscopy

Cell Type(s)
Cochlea