Technical Reference #824

824.

Activation Of Cytosolic Phospholipase A2 In Resident Peritoneal Macrophages By Listeria Monocytogenes Involves Listeriolysin O And Tlr2 Shahid Noor, Howard Goldfine, Dawn E. Tucker, Saritha Suram, Laurel L. Lenz, Shizuo Akira||, Satoshi Uematsu||, Milena Girotti**, Joseph V. Bonventre, Kevin Breuel, David L. Williams, and Christina C. Leslie, National Jewish Medical and Research Center, University of Pennsylvania, Osaka University, University of Colorado, Boulder, Brigham and Women's Hospital, Boston, ETSU Clinical Labs, University of Colorado School of Medicine, Aurora, The Journal of Biological Chemistry, 283(824), 4746, (2008)
Link To Paper

Abstract:
Eicosanoid production by macrophages is an early response to microbial infection that promotes acute inflammation. The intracellular pathogen Listeria monocytogenes stimulates arachidonic acid release and eicosanoid production from resident mouse peritone

Microscopic Technique
Fluorescence Microscopy

Cell Type(s)
Resident mouse peritoneal macrohpages