Technical Reference #676

Glass Bottom Culture Dishes

This study used MatTek product(s):

Citation in paper containing MatTek reference:
glass-bottom 35-mm petri dishes with 0.16- to 0.19-mm coverglasses (MatTek Corporation; Ashland;MA)

676.

A Surfactant Protein C Precursor Protein Brichos Domain Mutation Causes Endoplasmic Reticulum Stress Surafel Mulugeta; Vu Nguyen; Scott J. Russo; Madesh Muniswamy; and Michael F. Beers, University of Pennsylvania, American Journal of Respiratory Cell and Molecular Biology, 32(676), (2005)
Link To Paper

Abstract:
BRICHOS is a domain found in several proteins consisting of 100amino acids with sequence and structural similarities. Mutations inBRICHOS domain have been associated with both degenerative andproliferative diseases in several nonpulmonary organs alt

Keywords:
conformational disease; apoptosis; unfolded protein response; epithelial cells; protein aggregation

Materials & Methods:
For time-lapse microscopy the same procedure described above was followed with the exception of using glass-bottom 35-mm petri dishes with 0.16- to 0.19-mm coverglasses (MatTek Corporation AshlandMA) for live microscopic observation.

Microscopic Technique
Time Lapse Microscopy

Cell Type(s)
HEK-293