502 |
Hmg-Coa
Reductase Inhibitors Suppress Intracellular Calcium Mobilization And Membrane Current Induced
By Lysophosphatidylcholine In Endothelial Cells |
Keiko
Yokoyama, MD; Toshiyuki Ishibashi, MD; Hiroshi Ohkawara, MD; Junko Kimura, MD;
Isao Matsuoka, PhD; Takayuki Sakamoto, MD; Kenji Nagata, MD; Koichi Sugimoto, MD;
Sotaro Sakurada, MD; Yukio Maruyama, MD |
endothelium,
signal transduction, statins, calcium, ion channels |
[Ca2]i was measured as described
previously.10 Briefly, endothelial cells were grown to confluence in 35-mm glass-bottom dishes
(MatTek). The cells were incubated at 37°C for 10 minutes with 1mol/L fura-2/acetoxymethyl
ester and then washed with the
|
Inverted
Fluorescence Microscopy |
|
endothelial |
dendritic |
