Technical Reference #482

Glass Bottom Culture Dishes

This study used MatTek product(s):

Citation in paper containing MatTek reference:
Collagen I-coated okates with a glass bottom which were purchased from MatTek Corporation (Ashland; MA)

482.

Effect Of Tumor-Associated Mutant E-Cadherin Variants With Defects In Exons 8 Or 9 On Matrix Metalloproteinase 3 MARGIT FUCHS; CHRISTINE HERMANNSTA¨ DTER; KATJA SPECHT; PJOTR KNYAZEV; AXEL ULLRICH; ERIKA ROSIVATZ; RAYMONDE BUSCH; PETER HUTZLER; HEINZ HO¨ FLER; AND BIRGIT LUBER, Technische Universitat Munchen, The Journal of Cell Physiology, 202(482), (2005)
Link To Paper

Abstract:
Tumor progression is characterized by loss of cell adhesion and increase of invasion and metastasis. The cell adhesion moleculeE-cadherin is frequently down-regulated or mutated in tumors. In addition to down-regulation of cell adhesion degradation of

Keywords:
Tumor progression; cell adhesion; matrix metalloproteinase 3; E-cadherin; cell motility

Materials & Methods:
For time-lapse laser scanning microscopy cells were seeded at a density of 2105 cells per 3.5-cm in collagen I-coated plates with a glass bottom which were purchased from MatTek Corporation (Ashland MA). Uncoated plates were coated for 4hat 378Cwit

Microscopic Technique
Laser Scanning Microscopy, Time Lapse

Cell Type(s)
MDA-MB-435S