Technical Reference #433

433.

Biofilm Formation By The Fungal Pathogen Candida Albicans: Development; Architecture; And Drug Resistance JYOTSNA CHANDRA; DUNCAN M. KUHN; PRANAB K. MUKHERJEE; LOIS L. HOYER; THOMAS MCCORMICK; AND MAHMOUD A. GHANNOUM, University Hospitals of Cleveland, The Journal of Bacteriology, 183(433), (2001)
Link To Paper

Abstract:
Biofilms are a protected niche for microorganisms where they are safe from antibiotic treatment and cancreate a source of persistent infection. Using two clinically relevant Candida albicans biofilm models formed onbioprosthetic materials we demonst

Keywords:
Biofilms; antifungal

Materials & Methods:
After incubation with the dyes polymethylmethacrylate strips or silicone elastomer disks were flipped and placed on a 35-mm-diameter glass-bottom petri dish (MatTek Corp. Ashland Mass.). Stained biofilms were observed with a Zeiss LSM510 confocal sc

Microscopic Technique
Confocal Microscopy

Cell Type(s)
GDH-2436