Technical Reference #256

Glass Bottom Culture Dishes

This study used MatTek product(s):

Citation in paper containing MatTek reference:
Glass bottom tissue culture dishes were obtained from MatTek Corporation (Ashland; MA)

256.

Human Substance P Receptor Lacking The C-Terminal Domain Remains Competent To Desensitize And Internalize Richardson; M.D.; Baliusa; A.M.; Yamaguchia; K.; Freilicha; E.R.; Barakb; L.S.; Kwatraa; c; M.M.; Departments of a Anesthesiology and b Cell Biology; the Howard Hughes Medical Institute; and the c Department of Pharmacology and Cancer Biology; Duke Univ, HHMI, Journal of Neurochemistry, 84(256), (2003)
Link To Paper

Abstract:
Substance P receptor (SPR) and its naturally occurring splice-variant lacking the C-terminal tail are found in brain and spinal cord. Whether C-terminally truncated SPR desensitizes like full-length SPR is controversial. We used a multivaried approach t

Keywords:
ß-arrestin; desensitization; substance P receptor; internalization; phosphorylation

Microscopic Technique
Confocal Microscopy, Laser Scanning

Cell Type(s)
HEK-293