Technical Reference #1588

1588.

Binding Of Pdz Proteins To Hpv E6 Proteins Does Neither Correlate With Epidermiological Risk Classification Nore With The Immortalization Of Foreskin Keratinocytes Peter Muench; Thomas Hiller; Sonja Probst; Ana-Maria Florea; Frank Stubenrauch; Thomas Iftner, Universitaetsklinikum Tuebingen, Virology, 387(1588), (2009)

Abstract:
There is compelling evidence that high-risk human papillomaviruses (HPV) can cause cervical cancer.Strikingly HPV16 and 18 account for ∼70% of all cervical cancers whereas phylogenetically related types arefound at much lower frequencies. Most likel

Keywords:
HOV; MAGI1; hD1g; Risk classification; E6 protein; cervical cancer

Materials & Methods:
The E6 encoding plasmids used for in vitro transcription and translation have been previously described

Microscopic Technique
Fluorescence Microscopy, Immunofluorescence

Cell Type(s)
HEK-293