Technical Reference #1585

Glass Bottom Culture Dishes

This study used MatTek product(s):

Citation in paper containing MatTek reference:
Glass-bottomed culture dishes (35 mm) for microscopy were from MatTek Corporation; (Ashland; USA)

1585.

Cellular Uptake; Distribution And Cytotoxicity Of The Hydrophobic Cell Penetrating Peptide Sequence Pfvyli Linked To The Proapoptotic Domain Peptide Pad Catherine Watkins; Paul Brennan; Christopher Fegan; Kentan Takayama; Ikuhiko Nakase; Shiron Futaki; Arwyn T Jones, Cardiff University, Journal of Controlled Release, 140(1585), (2009)
Link To Paper

Abstract:
The capacity of cell penetrating peptides (CPPs) to breach biological membranes offers hope for theirutilisation as vectors for the delivery of small molecule drugs and macromolecular therapeutics. Using threedifferent cell systems including primary

Keywords:
cell penetrating peptides; octaarginine; proapoptotic domain; apoptosis; endocytosis

Materials & Methods:
Alexa Fluor® 488-C5-maleimide was purchased from Invitrogen

Microscopic Technique
Confocal Microscopy

Cell Type(s)
KG1A