Technical Reference #134

134.

Cellular Trafficking Of G Protein-Coupled Receptor/Β-Arrestin Endocytic Complexes. Zhang; J.; Barak; L.; Anborgh; P.; Laporte; S.; Caron; M.; and Ferguson; S, Duke University Medical Center; John P. Robarts Research Institute; University of Western Ontario, The Journal of Biological Chemistry, 274(134), (1999)
Link To Paper

Abstract:
β-Arrestins are multifunctional proteins identified on the basis of their ability to bind and uncouple G protein-coupled receptors (GPCR) from heterotrimeric G proteins. In addition β-arrestins play a central role in me-diating GPCR endocytosis a key re

Microscopic Technique
Confocal Microscopy

Cell Type(s)
HEK-293